Roddenberry played a variety of memorable characters, she was the cool and professional original Number One, the Nurse with bad taste in guys as Christine Chapel and the flighty yet crafty Betazed mother of ship's counselor Deanna Troi, Lwaxana Troi. Her TNG apperances were the most memorable because she got to play a comedic character and excelled at it. Though I had always wished they had kept Number One for the Original Series, that was a good character.
Her regular appearances in the various Star Trek series ensures she will be remembered though her best character was one that was offscreen. As the voice of the Enterprise computer, Roddenberry gave some personality to what was originally the only. thing. more. halting. than. William Shatner's. speech on the Original Series (It often started speeches with a bunch of tape sounds and the phrase "Wor-king"). As the Star Treks continued, the computer became more refined in its sound and recognizable as Roddenberry. Roddenberry's legacy will live on for one more Trek as the computer voice in the upcoming Star Trek XI.
Someone on You Tube posted a sort of "Enterprise computer's greatest hits" so I'll end with this clip. Majel Roddenberry has been referred to as "The First Lady of Star Trek" and the title suits her well. A sad day for Star Trek fans everywhere.
Majel Roddenberry / The Computer from Star Trek